3- Cell-growth factor
For whatever reason, some people have implicated in enlarged prostate that is a growth factor.
4- Mineral deficiency
Our prostate contains high amounts of zinc to function normally. Zinc deficiency causes the prostate to enlarge. This may be due to aging or uncontrolled diet with excessive alcohol drinking.
Study shows that uncontrolled diet that is high in saturated and trans fats are the main cause of hormone imbalance that results in prostate enlargement. Researchers suggest that excess calorie consumption could somehow directly stimulate prostate enlargement because the excess body fat that accumulates causes an imbalance of hormone levels.
Testosterone deficiency may be caused by high amounts of the by-product prolactin of testosterone of men in the body that stimulates even higher productions of the enzyme 5-alpha reductase resulting in a high amount of the conversion of testosterone to gihydro-testosterones DHT thus triggering prostate enlargement. Excess estrogen seems to be the culprit in prostate enlargement that leads to the pathology and favors the development of prostate cancer.